Sarah Haig

Postdoctoral Student

[email protected]

(734) 274-1298

http://www-personal.umich.edu/~sjhaig/index.html

Degrees

  • PhD in Civil and Environmental Engineering – Thesis title: “Characterizing the Functional Microbial Ecology of Slow Sand Filters Through Environmental Genomics” – University of Glasgow [2010- 2014].
  • MSci (Hons) with industrial placement in Microbiology – University of Glasgow [2005 -2010]

Work experience:

  • Post-doctoral research fellow in the Department of Civil & Environmental Engineering and Department of Pediatrics (University of Michigan) [2014 – present]
  • Research assistant at the laboratory of Dr. Robert Davies [Summer 2010]
  • Industrial placement at CEFAS (Weymouth, UK) [2008-2009]

Areas of Interest: My research combines environmental microbiology, environmental chemistry, and public health to advance water quality with a focus on drinking water systems. Specifically, I am interested in the development of novel technologies to detect degraders of emerging contaminants. I am also interested in designing new surface plumbing material to reduce pathogen growth, understanding the factors which influence antibiotic resistance and virulence in premise plumbing and exploring the ability to augment and manage existing microbial and macrobial communities within engineered systems to optimize performance.

Research Projects: I have been awarded a Microbiology of the Built Environment fellowship from the Alfred P. Sloan Foundation and a Dow sustainability fellowship to link the drinking water microbiome to human health.

My PhD. “Characterising the Functional Ecology of Slow Sand Filters Through Environmental Genomics.” focused on:

  • Sampling full-scale slow sand filters (SSFs) to determine the spatial and temporal changes in the microbial community.
  • Identifying and correlating specific microbial groups to water quality parameters and filter performance by using multivariate statistical analysis in combination with molecular data.
  • Investigating how SSFs remove pathogens by using DNA-SIP coupled with metagenomics.
  • Evaluating the potential of SSFs to remove emerging contaminants (e.g. estrogens) and determining if performance can be improved by bioaugmentation.

Previously I have worked on the phylogeny, virulence and serum-susceptibility of Yersinia ruckeri to Atlantic Salmon and Rainbow Trout. This work was carried out as part of an industrial placement at CEFAS. I have also worked on understanding the adherence mechanisms of Mannheimia haemolytica to ovine and bovine bronchial epithelial cells and organ cultures. Furthermore, I have worked on the biofilm forming potential of Pseudomonas aeruginosa on engineered surfaces.

Other Interests: In my spare time I love to bake, make candles and cook.

Honors and Awards: Microbiology of the Built Environment fellowship from the Alfred P. Sloan Foundation. Dow sustainability fellowship.

Peer Reviewed Journal Articles
:

  1. T. Olson, M. Wax, J. Yonts, K. Heidecorn, SJ. Haig, D. Yeoman, Z. Hayes, L. Raskin and B. Ellis. Forensic Estimates of Lead Release from Lead Service Lines during the Water Crisis in Flint, Michigan. Environmental Science & Technology Letters. 2017. [Impact Factor: 5.31].
  2. R.H. Lahr, H. Goetsch, SJ. Haig, N. Love, A. Noe-Hays, D. Aga, C. Bott, B. Foxman, J. Jimenez, T. Luo, R. Mullen, K. Nace, K. Ramadugu, K.R. Wigginton. Urine bacterial community convergence through fertilizer production: Storage, pasteurization, and struvite precipitation. Environmental Science & Technology. 50 (21), 11619-11626. 2016. [Impact Factor: 6.20].
  3. L.J. Caverly, L.A. Carmody, SJ. Haig, N. Kotlarz, L.M. Kalikin, L. Raskin, J.J. LiPuma. Culture- Independent Identification of Nontuberculous Mycobacteria in Cystic Fibrosis Respiratory Specimens. PLoS One. 11(4), p.e0153876. 2016. [Impact Factor: 3.54]
  4. SJ. Haig, C. Gauchotte-Lindsay, G. Collins and C. Quince. Bioaugmentation Mitigates the Impact of Estrogen on Coliform-Grazing Protozoa. Environmental Science & Technology. 50 (6), 3101-3110. 2016. [Impact Factor: 6.20]
  5. C.Quince, N.Loman, U.Z.Ijaz,A. M.Eren, D.Saulnier, J.Russell, SJ.Haig,et al., Extensive modulation of the fecal metagenome in children with Crohn’s disease during exclusive enteral nutrition. American Journal of Gastroenterology. 2015. [Impact Factor: 9.57]
  6. L. Caverly, T. Spilker, N. Kotlarz, SJ. Haig, L. Raskin, JJ. LiPuma. Improving Nontuberculous Mycobacterial DNA Extraction From CF Respiratory Samples. Pediatric Pulmonology. 50, 331. 2015. [Impact Factor: 2.85]
  7. SJ. Haig, C. Quince, R. Davies, C. Dorea and G. Collins. The Relationship Between Microbial Com- munity Evenness and Function in Slow Sand Filters. mBio. 6(5), e00729-15. 2015. [Impact Factor: 6.88]
  8. M. Feder, V. Phoenix, SJ. Haig, C. Dorea and H. Haynes. Influence of biofilms on heavy metal immobi- lization in Sustainable urban Drainage Systems (SuDS). Environmental Technology.June: 8, 1-12. 2015. [Impact Factor: 1.56]
  9. MJ. Khan, C. Quince, UJ, Ijaz, N. Loman, S.T. Calus, J. Quick, SJ. Haig, et al., A detailed analysis of the gut microbial diversity and metabolic activity in children with obesity of different aetiology and lean controls. Proceedings of the Nutrition Society. 72 (OCE1), E75. 2015. [Impact Factor: 4.42]
  10. SJ. Haig, M. Schirmer, R. D’Amore, J.Gibbs, R.L. Davies, G.Collins and C. Quince. Stable-Isotope Probing and Metagenomics Reveal Protozoan Grazing as the Major Route for E.coliRemoval in Slow Sand Filters. ISME Journal. 2014. [Impact Factor: 9.66]
  11. SJ. Haig, C. Quince, R. Davies, C. C. Dorea, and G. Collins. Validating the Performance and Microbial Community of Laboratory-Scale Slow Sand Filters with respect to Full-Scale Industrial Filters. Water Research 61, 141-151. 2014. [Impact Factor: 6.94]
  12. SJ. Haig, G. Collins, R. Davies, C. Dorea, and C. Quince. Biological aspects of slow sand filtration: past, present and future. Water Science & Technology: Water Supply, 11(4):468-472, 2011. [Impact Factor: 0.57]
  13. SJ. Haig. Adherence of Mannheimia haemolytica to ovine bronchial epithelial cells. Bioscience Hori- zons, 4(1):50, 2011. [Impact Factor: 0.32]
  14. D. Verner-Jeffreys, SJ. Haig, T. Welch, M. Pond, D. Stone, R. Davies, and R. Gardner. Characterisation of a serotype O1 Yersinia ruckeri isolate from the Isle of Man: further evidence that o antigen serotype is not a reliable indicator of virulence. European Association of Fish Pathologists, 31(3):8691, 2011. [Impact Factor: 0.54]
  15. SJ. Haig, R. Davies, T. Welch, R. Reese, and D. Verner-Jeffreys. Comparative susceptibility of Atlantic Salmon and Rainbow Trout to Yersinia ruckeri: relationship to O antigen serotype and resistance to serum killing. Veterinary Microbiology, 147(1-2):155-161, 2011. [Impact Factor: 2.63]
  16. D. Verner-Jeffreys, T. Welch, T. Schwarz, M. Pond, M. Woodward, SJ. Haig, G. Rimmer, E. Roberts, V. Morrison, and C. Baker-Austin. High prevalence of multidrug-tolerant bacteria and associated antimicrobial resistance genes isolated from ornamental fish and their carriage water. PLoS One, 4(12):e8388, 2009. [Impact Factor: 3.54]

Conference Presentations

  1. N. Kotlarz, SJ. Haig, B. Steglitz, L. Sanford, JJ. LiPuma, L. Raskin. Evaluation Of Selection For Op- portunistic Bacterial Pathogens During Biofiltration In Full-Scale Drinking Water Treatment Plant. To be presented at the American Water Works Association (AWWA) International Symposium on Biological Treatment. January 2018. [Oral]
  2. SJ. Haig, N. Kotlarz, L.M. Kalikin, L. Caverly, J.J LiPuma, L. Raskin. Are Opportunistic Pathogens in Premise Plumbing the Source of Infection in Children with Cystic Fibrosis? To be presented at the Microbiology of the built environment Symposium, Washington DC. October 2017. [Poster]
  3. Y. Shen, AJ. Prussin, SJ. Haig, L. Marr, L. Raskin. Quantification of opportunistic bacterial pathogens in hot water and aerosols formed during showering. To be presented at the Microbiology of the built environment Symposium, Washington DC. October 2017. [Poster]
  4. SJ. Haig, N. Kotlarz, L.M. Kalikin, L. Caverly, J.J LiPuma, L. Raskin. Searching for a Strain-Level Match: Is Drinking Water a Source of Clinically Relevant Cystic Fibrosis Opportunistic Bacterial Pathogens? Presented at the AEESP Conference, Ann Arbor, Michigan. June 2017. [Oral]
  5. N. Kotlarz, D. Berry, SJ. Haig, J.J LiPuma, L. Raskin. Mycobacteria Upregulate Intracellular Parasitism Genes in Response to the Drinking Water Disinfectant Monochloramine. Presented at the AEESP Con- ference, Ann Arbor, Michigan. June 2017. [Oral]
  6. Y. Shen, AJ. Prussin, SJ. Haig, L. Marr, L. Raskin. Quantification of opportunistic bacterial pathogens in hot water and aerosols formed during showering. Presented at the AEESP Conference, Ann Arbor, Michigan. June 2017. [Oral]
  7. Y. Shen, M. Wax, D. Yeoman, Z. Hayes, J. Yonts, SJ. Haig, N. Rockey, G. Burke, K. Heidecorn, J. Abernethy, E.Schwartz, B. Ellis, M. Kaufman, L. Raskin and T. Olson. Quantification of opportunistic bacterial pathogens and metal levels before and after lead service line replacement in Flint, Michigan. Presented at the AEESP Conference, Ann Arbor, Michigan. June 2017. [Oral]
  8. N. Kotlarz, D. Berry, SJ. Haig, J.J LiPuma, L. Raskin. Mycobacteria Upregulate Intracellular Parasitism Genes in Response to the Drinking Water Disinfectant Monochloramine. Presented at the UNC Water Microbiology Conference, Chapel Hill, North Carolina, May 2017. [Poster]
  9. M. Wax, D. Yeoman, Z. Hayes, J. Yonts, SJ. Haig, N. Rockey, G. Burke, K. Heidecorn, J. Abernethy, E.Schwartz, B. Ellis, M. Kaufman, L. Raskin and T. Olson. Water quality characteristics before and after lead service line replacement in Flint, Michigan. Presented at the AWWA International Symposium on Inorganics, Detroit, Michigan, March 2017. [Poster]
  10. SJ. Haig, N. Kotlarz, N. Rockey, L.M. Kalikin, L. Caverly, J.J LiPuma, L. Raskin. Residence Time, Pipe Material and Chemical Parameters Impact the Occurrence of Opportunistic Pathogens and Antibiotic Resistance Genes in Drinking Water. Presented at the Borchardt Conference, Ann Arbor, Michigan. February 2017. [Poster]
  11. N.Kotlarz,N.Rockey,T.M.Olson,SJ.Haig,L.Sanford,J.JLiPuma,L.Raskin.OpportunisticPathogenic Bacteria Survive Ozone Disinfection: Observations from a Full-Scale Drinking Water Treatment Plant. Presented at the Borchardt Conference, Ann Arbor, Michigan. February 2017. [Oral]
  12. G. Burke, D. Yeoman, Z. Hayes, SJ. Haig, Y. Shen, J. Yonts, M. Wax, N. Rockey, M. Kaufman, L. Raskin, and T. Olsen. Water quality characteristics before and after lead service line replacement in Flint, Michigan, Presented at the Borchardt Conference, Ann Arbor, Michigan. February 2017. [Poster]
  13. SJ. Haig, N. Kotlarz, N. Rockey, L.M. Kalikin, L.J. Caverly, J.J. LiPuma, L. Raskin. From Source to Tap: Linking the Drinking Water Microbiome to The Respiratory Tract Microbiome. Presented at the Water Quality Technology Conference, Indianapolis, Indiana, November 2016. [Oral]
  14. N. Rockey, J. Yonts, SJ. Haig, K. Wigginton, L. Raskin. Abundance of Opportunistic Bacterial Pathogens in a Domestic Potable Hot Water Pipe Loop System. Presented at the Water Quality Technology Confer- ence, Indianapolis, Indiana, November 2016. [Oral]
  15. J. Yonts, J. Christopher, N. Rockey, SJ. Haig, N. Kotlarz, R. Corona, M.Willett, K. Wigginton, L. Raskin. Corrosion Cause Determination and Control Strategies within a Centralized Domestic Hot Water System. Presented at the Water Quality Technology Conference, Indianapolis, Indiana, November 2016. [Poster]
  16. SJ. Haig, N. Kotlarz, N. Rockey, L.M. Kalikin, L.J. Caverly, J.J. LiPuma, L. Raskin. Stagnation Time, Pipe Material and Chemical Parameters Impact The Occurrence of Opportunistic Respiratory Pathogens in Drinking Water. Presented at the IWA Specialist Conference: Microbial Ecology in Water Engineering & Biofilms, Copenhagen, Denmark, September 2016. [Oral]
  17. SJ. Haig, J. Yonts, N. Rockey, G. Burke, D. Yeoman, Z. Hayes, B. Eggleston, B. Warner, C. Wilhelm, B. Ellis, K. Wigginton, M. Kaufman, T. Olson, and L. Raskin. Linking opportunistic bacterial pathogens and metal levels in drinking water samples and corroded service lines in Flint, Michigan, USA, Presented at the IWA Specialist Conference: Microbial Ecology in Water Engineering & Biofilms, Copenhagen, Denmark, September 2016. [Poster]
  18. N. Kotlarz, N. Rockey, SJ. Haig, J.J. LiPuma, L. Raskin. Full-Scale Ozonation of Drinking Water Micro- bial Communities. Presented at the IWA Microbial Ecology in Water Engineering & Biofilms conference, Copenhagen, Denmark, September 2016. [Poster]
  19. SJ. Haig, N. Kotlarz, N. Rockey, L.M. Kalikin, L.J. Caverly, J.J. LiPuma, L. Raskin. Linking the preva- lence of opportunistic respiratory pathogens to physical and chemical characteristics in drinking water systems. Presented at the Alfred P. Sloan Foundation 5th Annual Microbiology of the Built Environment Conference, Boulder, Colorado, June 2016. [Oral]
  20. SJ. Haig, N. Kotlarz, N. Rockey, J. Yonts, W. Wigginton, J.J. LiPuma, L. Raskin. From Source to Tap: Linking Drinking Water Microbiomes to Human Health. Presented at the Alfred P. Sloan Foundation 5th Annual Microbiology of the Built Environment Conference, Boulder, Colorado, June 2016. [Poster]
  21. N. Rockey, J. Yonts, SJ. Haig, K. Wigginton, L. Raskin. Opportunistic Pathogens in a Hot Water Pipe Loop System. Presented at the Water Microbiology Conference, Chapel Hill, North Carolina, May 2016. [Poster]
  22. L.J. Caverly, SJ. Haig, N. Kotlarz, L. Raskin, J.J. LiPuma. Improving Nontuberculosis Mycobacte- rial DNA Extraction From CF Respiratory Samples. Presented at the North American CF conference, Phoenix, Arizona, October 2015. [Poster]
  23. N. Kotlarz, SJ. Haig, J. Yonts, J. LiPuma and L. Raskin. Environmental Mycobacteria in Chlorami- nated Drinking Water. Presented at the IWA Biofilms in Drinking Water Systems: from treatment to tap conference, Arosa, Switzerland, August 2015. [Oral]
  24. SJ. Haig N. Kotlarz, J.LiPuma, L. Raskin. From Source to Tap: Linking the Drinking Water Microbiome to Human Health. Presented at the 4th Sloan Foundation Conference, Boulder, Colorado, July 2015. [Oral]
  25. N. Kotlarz, SJ. Haig, J. LiPuma and L. Raskin. Nucleic Acid Extractions from Mycobacteria in Drinking Water Systems Presented at the AEESP Conference, New Haven, Connecticut, June 2015. [Poster]
  26. N. Kotlarz, SJ. Haig, J. LiPuma and L. Raskin. Nucleic Acid Extractions from Mycobacteria in Drinking Water Systems Presented at the ASM Conference, New Orleans, Louisiana, May 2015. [Oral]
  27. SJ. Haig, G. Collins, R. Davies, C. Quince and C. Gauchotte-Lindsay. Bioaugmentation Reduces the Negative Effects that Estrogen Exposure has on the Pathogen Removal Capacity of Slow Sand Filters. Presented at the 15th ISME Conference, Seoul, South Korea, August 2014. [Poster]
  28. SJ. Haig, G. Collins, R. Davies, C. Quince and C. Gauchotte-Lindsay. Bioaugmentation reduces negative effect of estrogens on coliform removal in slow sand filters. Presented at the 5th International Slow and Alternative Biological Filtration Conference, Nagoya, Japan, June 2014. [Oral]
  29. SJ. Haig, G. Collins, R. Davies, and C. Quince. Exploring Coliform Removal in Slow Sand Filters using DNA-SIP Coupled with Metagenomics. Presented at Microbial Ecology in Water Engineering (MEWE), Ann Arbor, Michigan, July 2013. [Oral]
  30. SJ. Haig, G. Collins, R. Davies, and C. Quince. Pathogen removal in slow sand filters as revealed by stable isotope probing coupled with next generation sequencing. Presented at International Society for Microbial Ecology (ISME), Copenhagen, Denmark, August 2012. [Oral]
  31. SJ. Haig, C. Dorea, G. Collins, R. Davies, and C. Quince. Validating Laboratory Slow Sand Filtration Studies Through Water Quality and Molecular Analysis. Presented at Particle Separation, Berlin, Germany, June 2012. [Oral]
  32. SJ. Haig, G. Collins, R. Davies, C. Dorea, and C. Quince. Biological aspects of slow sand filtration: past, present and future. Presented at UK National Young Water Professionals, Edinburgh, Scotland, April 2011. [Poster]

Contact Information

1351 Beal Avenue, 219 EWRE, Ann Arbor, MI 48108,

Twitter: SarahJaneHaig,